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    Scientists once believed that stress could make inflammatory bowel disease worse, and managing stress was an important part of treatment. Proving the relationship between psychological factors and a disease's progression can be difficult. However, when later studies failed to establish this connection, scientists focused on environmental triggers and genetic susceptibility to inflammation as possible causes.

    Thanks to continued research regarding the relationship between stress and other chronic inflammatory conditions and the realization that existing literature is insufficient to exclude stress as a possible cause of IBD, researchers are again exploring this issue.

    A recent study by Canadian researchers from McMaster University and Hamilton Health Sciences Corporation in Hamilton, Ontario, which was published in the October 1999 issue of "Nature Medicine," appears to establish this link.

    These researchers used a substance called DNBS to cause mice to develop colitis. Initially they gave the mice two milligrams of DNBS and noted that it had no effect on the mice. When they administered six milligrams of DNBS, however, the mice developed severe colitis that lasted several weeks but resolved by six weeks. The mice were then confined and subjected to loud noise twice daily for five days. Immediately after the last noise exposure scientists again gave the mice two milligrams of DNBS and the mice again developed severe colitis. These researchers, therefore, concluded that stress produced changes in these mice that made them susceptible to amounts of DNBS that previously had no effect. They believe that stress management needs to be included in the treatment of IBD. is not a comercial or official site. all opinions provided at drugsboat are personal opinions and should not be taken too seriously, but considered. drugsboat holds no responsibility for any negative consequences of it's contents. information is here free for taking, it's visitor's responsibility to use it in a proper way.